Sabrina Paganoni, MD, PhD
Not currently accepting new patients
4.985965 average rating from 57 patient reviews
Specialties
Affiliation
Mass General Brigham
Provider Locations
- Boston, MA
Dr. Paganoni is a physician-scientist at the Sean M. Healey & AMG Center for Integrated ALS Care and Discovery at Mass General Brigham, where she serves as the Robert H. Brown, Jr., MD, PhD Endowed Chair in Neurology and Co-Director of the Neurological Clinical Research Institute. She is also an Associate Professor at Harvard Medical School. She specializes in neuromuscular medicine and cares for people living with ALS (amyotrophic lateral sclerosis), primary lateral sclerosis (PLS), and other motor neuron diseases. Dr. Paganoni completed medical school at the University of Milan, earned a PhD in Neuroscience from Northwestern University, and completed her residency and fellowship training at Mass General Brigham/Harvard Medical School. Her research focuses on developing new treatments for ALS by leading innovative clinical trials and expanding access to clinical research opportunities. She is also committed to advancing patient care through the development of new assistive technologies and innovative models of care for people living with ALS and related conditions.
Education & Training
- Fellowship: Brigham and Women's Hospital, Neuromuscular Disease, 2013
- Fellowship: Mass General Brigham Combined Training Program, Neuromuscular Medicine, 2012
- Residency: Spaulding Rehabilitation Hospital, Physical Medicine & Rehab, 2011
- Internship: Weiss Memorial Hospital, Internal Medicine, 2008
- Internship: University of Milan, 2000
- Medical Education: University of Milan-Medical School, 1999
Board Certifications
- Physical Medicine and Rehabilitation, American Board of Physical Medicine and Rehabilitation
- Neuromuscular Medicine, American Board of Physical Medicine and Rehabilitation
Languages Spoken
- Italian
- English
Age Group Treated
- Adults
Patient Feedback
4.985965 average rating from 57 reviews
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The doctor is very pleasant, caring and responsive.
2026-08-15
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Hi, I had an excellent experience with Dr. Paganoni and the other members of the staff at Mass General for my visit last week. I felt very informed and am very confident in moving my care to Mass General ALS Clinic for further treatment and evaluation of my case. I was extremely comfortable and very satisfied with my first visit at the hospital.
2026-08-12
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Dr Paganoni introduced herself and then proceeded to take extreme care in gathering the threads of my early symptoms in order to weave together an accurate timeline of the onset of my disease. My local neurologist did a thorough job of ordering all the tests needed to give him a diagnosis and wrote unspecified motor neuron disease. I did not realize that translated to ALS. Dr Paganoni order more tests for a second visit to MGB to verify those results. [redacted] That confusion was cleared up on my second visit with Dr Paganoni just a week after my first appointment when she was relaying information about the disease and I asked "Do I have ALS"?" I'm sure she was unaware of my naivety on the subject. She was extremely kind in her response and said I was in the early stages of this disease. She had arranged for a team to see me that day. I met with a nurse, respiratory specialist and physical therapist. There's an old comic strip about a student raising his hand in class and saying, " My brain is full, may I be excused please?" I instantly thought of that as I was given new information about new prescriptions and B12 shots being ordered for me, physical therapy being arranged, brace fittings and a ton of information about community outreach and clinical research and patient opportunities. I initially was overwhelmed, exhausted from the travel and willing my stomach and nerves to calm down. And after a beat I realized Dr Paganoni knows that when a patient is back in their own environment that she has provided them a perfect road map. I have a clear and immediate plan that was made for me. I am ticking those boxes one by one and know what I need to do for the immediate future. I am just at the beginning of this process and I am extremely grateful that I was referred to Dr Paganoni and her team to guide me down the long road.
2026-08-13
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Dr Paganoni is a wonderful, committed person who is extremely experienced in ALS. Despite being engaged in so many aspects of the disease she always makes the appointment thorough and never fails to give her total attention to you.
2026-07-13
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Every interaction with her is marked by respect and attention.
2026-07-12
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Very good as always ?
2026-05-17
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Great
2026-05-12
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Trip to Mass Genn was great
2026-05-05
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Job well done!!!
2026-03-29
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Dr. Paganoni was knowledgeable, kind, thorough and compassionate. I felt heard and cared for. Even though I was seen at the clinic for a second opinion and not as a longterm patient, I was treated as though I were a longterm patient and left feeling comfortable with reaching out for follow-up guidance. If I lived closer, I would opt to receive all of my care here. But with the MGB team working with my neurologist in Worcester, I feel like I will get the care I need.
2026-03-28
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i am so glad we have this team
2026-03-28
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They were all amazing. I enjoyed the visit and every nurse, doctors, they all were very understanding and very kind. I thought they were beautiful people. Thank you. They're very professional, very professional. I thought they were awesome. All right. Thank you.
2026-03-04
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Excellent
2026-03-01
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Excellent communicator, friendly and respectful. Very thorough and good at expressing reasons for various tests..
2026-02-15
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She is very warm, caring and concerned.
2026-02-09
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Extremely professional, understanding and caring experience.
2026-02-08
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I genuinely appreciated the time you took to listen to me and provide follow-up care. This goes a long way when dealing with health issues, knowing that you were truly understood.
2026-02-01
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This was my first visit. I was treated with care and respect.
2026-01-12
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The care provider was extremely supportive and professional.
2026-01-12
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Very knowledgeable and professional about ALS. As a first time patient with ALS it can be very challenging to understand everything about what the total picture is. The team made it easy to understand and provide a better understanding leading to hope that there are many ways to improve the situation.
2025-12-14
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I thought she was wonderful. She was kind and caring and respectful and I feel very fortunate that I have that doctor to be on my team and to take care of me.
2025-12-11
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She was always very easy to talk to, very kind, you could relate to her, and very informative. She'd listen to our questions, we could ask any type of questions, and then she'd give her feedback and tell us what she thought. She was absolutely amazing. Thank you.
2025-12-11
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She's the best.
2025-11-20
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she took the time to explain things clearly. she listened well and answered all my questions. she knows her area of expertise perfectly.
2025-11-10
Accepted Insurance
- Tufts Medicare Preferred
- Wellpoint
- WellSense
- Medicaid RI
- Blue Cross Blue Shield
- Multiplan
- Tufts Health Plan
- Harvard Pilgrim Health Care
- Commonwealth Care Alliance
- Blue Cross Blue Shield - Indemnity
- MassHealth
- Medicaid ME
- Senior Whole Health
- Medicare
- TriCare
- Mass General Brigham Health Plan
- Medicaid NH
- Beech Street
- Cigna
- Aetna
- WellSense NH
- Medicaid VT
- Blue Cross Blue Shield Medicare
- Maine Community Health Options
- Coventry
- United Health Care
- Humana
- Railroad Medicare
- Fallon Health