David Brian Sykes, MD, PhD

Patient Feedback

4.952 average rating from 225 reviews

• Thanks.

  2026-07-08

• Doctor was great (as usual) and nurse (without me asking) offered me a bottle of water, which was much appreciated.

  2026-07-08

• He listened to my concerns and wanted to know my intire medical history. Explained both long and short term treatment. Was caring and " human ". A nice guy...

  2026-07-05

• I was very impressed with Dr. Sykes. He has in-depth knowledge of the problem I had as well as all related issues. We have a very good discussion of my situation and the potential treatments.

  2026-06-30

• Excellent Experience found info about my blood.

  2026-06-27

• Dr. Sykes was very thorough, very patient, explained things excellently and was patient and thorough with my questions and helped me or informed me to make a good decision about my care.

  2026-06-24

• [redacted] it was a great experience to get my second opinion from Dr. Sykes!

  2026-06-22

• I felt my care was in good hands.

  2026-06-22

• Outstanding!

  2026-06-22

• Dr. Sykes was wonderful! He drew me diagrams and I was able to take them home. He explained things to my family member and me in a way that we could both understand. He was very reasonable and knowledgeable and I truly appreciated him consulting on my case.

  2026-06-20

• Very professional, caring, and knowledgeable. Rate very high

  2026-06-07

• He is the BEST, very patient , knowledgeable, kind and reassuring !

  2026-06-06

• Dr. Sykes is very professional, even- keeled and a great guy. From walking into Hematology from the folks at the front desk to the assistant who took me in to the woman who made my next appointment everything works well. All great individuals. In fact, I have had nothing but great experiences at MGH and their affiliates (knock on wood).

  2026-05-27

• Dr Sykes is a very great doctor. He provides useful information on various hematology topics and their relationships to other relevant health concerns. He treats patients with respect and has a very patient and professional approach while demonstrating a good bedside manner.

  2026-05-27

• He was especially kind and very prepared for our visit. My daughter most likely has the same bleeding issue and she works at MGB in Boston. I would be very happy if he was her doctor.

  2026-05-27

• I'm totally at ease with him after only two visits. So approachable, patient, knowledgeable and kind. I always leave with my questions answered to the greatest possible extent and with a game plan he's guided me through. Truly one of the best.

  2026-05-28

• David Sykes is caring, knowledgeable and considerate. He listens, honors my concerns and yet is firm in his recommendations that cannot be compromised. I know he has my best health in mind, so I trust his judgment and learn a lot about my hematological condition. After our appointment, I always feel better and more positive about my prognosis.

  2026-05-26

• Dr Sykes is great provider. He listens carefully, explains what is going on with my condition and further explains what I'd needed to keep on track and keep my anemia under control

  2026-05-25

• Dr. David Sykes was outstanding. He had reviewed my entire chart. He was smart, confident, friendly and knowledgeable. I would recommend him to my friends and family without hesitation. A wonderful man.

  2026-05-24

• Just say Dr. Sykes is excellent.

  2026-05-21

• My experience was of the highest level of professionalism, understanding, and care

  2026-05-14

• Attentive, caring, knowledgeable, friendly. Welcomed my input in shared conversation and communication. Among the best of "bedside manners" ever encountered.

  2026-05-12

• Dr. Skykes is absolutely one of the best doctors I have had the privilege to be in his care. He is absolutely brilliant and yet down to earth. He is a true professional- please thank him for me. [redacted]

  2026-05-10

• Always a good experience

  2026-05-06

• Dr. Sykes was great. So friendly and informative. He put my wife and I at ease throughout our visit. He took the time to explain his analysis of my existing medical history as well as the additional test he would like to perform. We feel very grateful to have Dr. Sykes following my medical care.

  2026-05-04

• Dr. Sykes is the best!

  2026-04-20

• Dr. Sykes has always explained my condition in a way that I definitely understand. With this knowledge , I can make decisions re my health. He has a nice kind manner. I feel fortunate to have him as my Dr.

  2026-04-16

• I was seen in a timely manner and the doctor was very clear and patient with how he explained things and he listened to what I had to say. Very happy with the visit!

  2026-04-13

• A continued follow up visit re: rbc issue. Had patched in my sister-in-law via phone. Everything looks fairly stable, thus no need for any immediate treatments. To be followed in another 6 months unless I feel more immediate look see.

  2026-04-13

• I came from Virginia to get treated as my drs. In Virginia couldn't figure out my issues. The provider at MGH was very kind an explained all results.

  2026-04-12

• The provider was very professional and knowledgeable about my case. His staff was also very professional and impressive. I am glad they all attended to me .

  2026-04-02

• Very professional

  2026-03-30

• Dr. Sykes was exceptional in his ability to communicate clearly about my concerns. He is unrushed, caring and personable, yet also quick and efficient.

  2026-03-30

• Dr. David is very respectful and a good listener. Supportive. He reassured me about my problem, and he promised to follow up on my condition in the future.

  2026-03-26

• Dr. David Sykes is the best of the best. So is the Fellow who worked with him. Dr. Sykes really put my mind at ease. I really learned a lot and I feel like we have a plan. I cannot thank him enough.

  2026-03-26

• I am very lucky to have found this provider

  2026-03-22

• The care at the hospital and the medical staff were excellent. Everything was excellent. Thank you very much.

  2026-03-25

• This doctor had more information about my past history, my blood test that had been done just hours before, and it was overall a 10 appointment.

  2026-03-20

• Dr. Sykes is the best doctor I have ever had. When I had 2 surgical procedures between visits, he reached out to each surgeon to ensure they understood my Hematology history. He asks for my input and he listens and cares. He's the best!

  2026-03-16

• Dr. Sykes is the best! God's gift to his profession! Truly! I can't say enough good things about him!

  2026-03-15

• Dr. Sykes is phenomenal. He clarified my misunderstandings about my condition and made sure that I had accurate information. One thing I really appreciate is that he took the time to write down my medical dx and his penmanship is legible. He said if I had any other questions after I leave I can contact him. He escorted me out of the office to the lab. I had assumed that I would need to go to the Wang building for bloodwork. I also had a standing order for bloodwork from another MD, and he graciously agreed it to his bloodwork.

  2026-03-15

• Everyone was very kind, pleasant, and informative.

  2026-03-11

• I really appreciate his kndness and dedication to my care.

  2026-03-13

• Excellent, very kind

  2026-03-12

• Always have a great experience great doctor listen and explain any concern I may have

  2026-03-08

• Dr.Sykes was very informative

  2026-03-04

• Professional, understanding, interested in all prior issues and information provided via the portal before my appointment.

  2026-03-04

• Dr Sykes is the best, his bedside manner is what doctors should aspire to

  2026-03-02

• Dr. Sykes was very thorough learning my history. He explored many avenues related to my medical condition and the referral to him. We addressed next steps and he will be following up with me when all results are available after my upcoming surgery. This consultation was requested by my surgeon for Dr. Sykes input. I know he has personally spoken to my surgeron as well regarding the referral and results. All of the staff was friendly, accommodating, and professional during my visit and performing all the tests I needed while in the office.

  2026-02-17

• Dr Sykes is the best!!

  2026-02-16

• I can't say enough good things about Dr. Sykes. He was excellent and he has been excellent.

  2026-02-18

• Dr. Sykes is very, very knowledgeable. He pays attention to you. He gives his time. He asks you questions. He is excellent. Thank you very much for the opportunity. Thank you.

  2026-02-13

• I cannot speak more highly of Dr. Sykes. This was an initial visit to discuss labs he had ordered and to discuss my recent history of symptoms which began just over a year ago, and the possibility of blood disorders that two of my siblings have been diagnosed with. Dr. Sykes explained in detail, the results of the bloodwork he had ordered and though he was reassuring that my results were relatively good, he asked so many questions and truly listened to me. With the information we exchanged in this one office visit, he provided me with more optimism than I've had in many months. He offered a few other possibilities for the symptoms I am experiencing [redacted] I am so grateful for having met Dr. Sykes. I feel confident in his expertise and yet his kindness and compassion is unsurpassed. [redacted]

  2026-02-02

• From the (2) Women at the Front desk Awesome bye the way, to the Nurse, and then the Visit and chat with the Dr, whom personally walked me to the Blood center, then the wonderful person whom drawn my blood, MGH is the BESY

  2026-02-02

• Dr. Sykes took the time to understand my situation and offer possible solutions.

  2026-02-03

• Great medical experience for me. Super knowledgeable. Extremely helpful. Read my medical history before I got to the appt.

  2026-02-02

• Great MD

  2026-01-29

• Great knowledgeable and spoke in language any person can understand.

  2026-01-29

• Dr. Sykes is a caring doctor. He is very interested in my care and he is making sure to look at every piece of my medical puzzle; to keep me in a good range and help me improve. He is an amazing doctor and shows such passion and interest in me. There is no one better.

  2026-01-28

• Excellent doctor

  2026-01-19

• Dr Sykes is a warm caring physician and a credit to his specialty and to mass general

  2026-01-15

• As all my questions answered for me, I thought he was a very thoughtful provider and he was extremely well prepared for being given over my record in great detail and really thought about it. I would give women A+, I couldn't imagine a better provider

  2026-01-14

• He is the best.....continues to encourage questions and updates me on any new modalities, medications and research progress pertaining to my diagnosis. My doctor always reiterates the important of communicating any concerns/questions that I have about my progress.

  2026-01-11

• Dr Sykes is the most thoughtful, engaged, caring and knowledgeable provider. I am truly grateful to be under his care and trust his expertise in my autoimmune disease. I wish all medical professionals were as dedicated and professional. Thank you!!!

  2025-12-29

• Yes, Dr. Sykes was very thorough, compassionate. He listened to all the complexities of my situation. He gave good thorough responses. I was very comfortable with his treatment. I would definitely recommend him to anybody.

  2025-12-24

• My family and I would like to greatly express our thanks to Dr. Sykes. We think he's fantastic. With my current medical conditions, I've seen many doctors over the years, some of the best right here at Mass General and the Brigham as well. And Dr. Sykes is amongst the top of the top. He is fantastic. And my current disease is a very challenging one. He's helped us to learn so much over this last year and really get the help that we need to improve my treatment, prolong my life. And my family and I are extremely grateful for having doctors like him. I can't say enough good things about him.

  2025-12-24

• Provider a scholar and a gentleman MA could improve patient interaction skills

  2025-12-21

• Dr. Skyes explained my condition in a way no other provider has done. I left the office feeling more confident in the management of my condition and more positive regarding the outcome.

  2025-12-20

• The provider was very nice and talked to me everything.

  2025-12-19

• This was our first visit to the office and it was a wonderful visit. The provider explained my condition in a way I could have understand. He was very patient and answered all out questions. I am so happy we decided on Mass General for care.

  2025-12-17

• Extremely knowledgeable and thoughtful

  2025-12-16

• My visit was very satisfactory, excellent care from Dr. Sykes. I was happy to have his professional care.

  2025-11-30

• The whole team is amazing, compassionate and helpful.

  2025-11-26

• Knowledgeable, thorough, and very accommodating assisting me with arranging my ongoing treatment schedule at Cape Cod Hospital after having my first treatment completed at the MGH Transfusion Services unit.

  2025-11-25

• Dr. Sykes was so caring, knowledgeable, and patient during our visit. Even though it was a virtual consult, he was very compassionate and an excellent listener. He addressed every single one of my concerns and explained things in a way that made sense to a layperson. A truly great doctor!

  2025-11-20

• Dr Sykes has the best temperament and has always put me at ease-which is remarkable when you walk into the Cancer center initially. He is very adroit at relating the specific tests and what they represent and how they factor into your overall health. You almost forget he is as accomplished as he is. No agenda, except relating to you why you are there and what he is watching and why. He is certainly someone who enjoys talking to people which isn't always the case with specialists. MGH couldn't have done better with anyone else.

  2025-11-19

• I was delighted with the medical care I received from Dr. Sykes. I couldn't have felt in better hands. Many thanks to him and his wonderful personality.

  2025-11-21

• He was, to the point, he asked me a lot of questions, he came up with 2 or 3 treatment plan and was meticulous with each plan.

  2025-11-19

• He had an open and friendly manner and answered all my questions clearly. I never felt rushed, and he was prompt in providing a report with precisely the type of information I needed;for this consult.

  2025-11-17

• He is a good listener and explainer. He spoke to me like I was intelligent and could understand. I left with a clear understanding about my diagnosis.

  2025-11-10

• Great provider [redacted}

  2025-11-09

• Dr. Sykes is simply the best in every respect. I am so fortunate to be his patient. Thank you, Dr. Sykes!

  2025-11-05

• Dr. Sykes explained everything clearly, being sure that I understood what he was saying. He followed up with a message through the portal and a telephone call telling me to modify the medication. I am glad to continue as his patient.

  2025-11-04

• This provider was incredible. Knowledgeable, respectful, great communication, listened to what I had to say. Explained in laymen terms. There is nothing but extreme positives with Dr Sykes

  2025-11-03

• Dealing with Dr. Sykes is such a pleasure. He is kind considerate listens to you and is always right there on the ball. There is no time lapse or anything. He takes care of you immediately and always. We need 100,000 more docs like him and the world would be a better place. Thank you.

  2025-10-29

• It was very comfortable and an overall enjoyable visit

  2025-10-30

• We were completely understood about My father's illness. And future plan of his medication and all which give us big relief. We are really grateful

  2025-10-23

• Excellent!!!

  2025-10-22

• Very professional, yet personable team in this department. Working with any of the staff at MGH Boston or Waltham has been a pleasant experience, considering other medical centers.

  2025-10-22

• Dr. Sykes was excellent. He was thoughtful, explained everything clearly, and I wish all providers were as good as he.

  2025-10-19

• Excellent

  2025-10-15

• It was terrifi and I learned a great deal from Provider and the Fellow!

  2025-10-14

• Very good experience with Dr. Sykes. It was sort of a consultative visit re: low red blood cell count, a one off type visit. One of the residents working with him reviewed history etc. initially and then briefed Dr. He explained situation in a very concise manner using a sheet of paper to outline what's going on, options to treat etc. It was most helpful. Very engaging Dr. and Dr. visit. Left there with a much better understanding of the condition and a follow up visit with blood work is scheduled.

  2025-10-08

• I want to thank you for the professional and humane attention you gave me. May God bless you always for being so attentive to my needs, and for making me feel like a family.

  2025-10-07

• The experience was wonderful from the start. The staff was friendly and professional. Always a pleasure in this office.

  2025-10-01

• Dr.Sykes was great. He explained all of my blood readings in a manner that I easily understood. He answered my questions explaining everything in a manner that I completely understood.

  2025-09-28

• all good

  2025-09-24

• This was my first visit with Dr. Sykes and I am very pleased.

  2025-09-26

• Dr. Sykes is an extremely caring doctor. He explains things well. He keeps me informed. And I like him a lot. Thank you.

  2025-09-24

• Excellent

  2025-09-21

• Dr. Sykes is the best there is. He knows every aspect of my health and cares about how various health issues may impact each other. Dr. Sykes is my go-to doctor when I need help and he's always there. I can't thank him enough for all he does. Thank you!

  2025-09-14

• I couldn't be in the hands of anyone more confident or compassionate than Dr. Sykes.

  2025-09-11

• That was the first time I met the doctor. I was very pleased to find him such a pleasure.

  2025-08-27

• Great experience!

  2025-08-25