Matthew R Smith, MD, PhD

Matthew R Smith, MD, PhD

Not currently accepting new patients

4.945349 average rating from 344 patient reviews

Specialties

Affiliation

Mass General Brigham

Provider Locations

  • Waltham, MA
  • Boston, MA

Dr. Matthew R. Smith is Director of the Genitourinary Oncology Program at Massachusetts General Hospital Cancer Center and an Associate Professor of Medicine at Harvard Medical School. He graduated summa cum laude from Canisius College with a B.A. in biochemistry. He received his MD and PhD degrees from Duke University School of Medicine. He trained in Internal Medicine at Brigham and Women's Hospital. He completed a fellowship in Medical Oncology at Dana Farber Cancer Institute and a postdoctoral fellowship at Massachusetts Institute of Technology.

He is an internationally recognized expert in prostate cancer. He has published extensively on treatment and prevention of bone metastases and prostate cancer survivorship. He has authored more than 150 peer-reviewed articles including manuscripts in New England Journal of Medicine, Journal of Clinical Oncology, Cancer, Journal of Clinical Endocrinology and Metabolism, and Clinical Cancer Research. His research is supported by competitive grants and awards from the National Institutes of Health, Lance Armstrong Foundation Research Award, and the Prostate Cancer Foundation.

Education & Training

  • Fellowship: Dana Farber Cancer Institute*, Medical Oncology, 1997
  • Internship: Brigham and Women's Hospital, Internal Medicine, 1994
  • Residency: Brigham and Women's Hospital, Internal Medicine, 1994
  • Medical Education: Duke University School of Medicine, 1992

Board Certifications

  • Medical Oncology, American Board of Internal Medicine

Languages Spoken

  • English

Age Group Treated

  • Adults

Patient Feedback

4.945349 average rating from 344 reviews

  • Dr. Matthew Smith is the best doctor I ever had

    2026-07-01

  • Very pleasant follow up visit

    2026-07-01

  • I am very pleased to have Dr. Smith as my provider. He is knowledgeable and respectful.

    2026-07-01

  • Dr. Smith is a compassionate, knowledgeable clinician. I am grateful for his expertise, advice and medical care.

    2026-07-01

  • Dr Smith was on the team that treated my prostate cancer 20 yrs ago so his perspective and ability to access that old information proved valuable.

    2026-06-27

  • He's the best. He's keeping me alive. I have the upmost faith in him.

    2026-06-27

  • The provider and I have seen each other for years. He is the best.

    2026-06-24

  • My experience at Mass General has always been a great experience when I go there. I am so amazed at how many people are sick when I walk in that front door and they're all taken care of with 100% care day and a day out they all do a great job

    2026-06-24

  • Everyone under Dr Smith has been extremely professional and rather soothing during a tense time.

    2026-06-24

  • Everything was excellent!

    2026-06-24

  • I was impressed how the nurses worked as a team.

    2026-06-22

  • Dr. Smith is a very caring doctor. He's been treating my cancer for a long time. He's got it under remission and he's controlling that wonderfully. I'm very, very happy with him. I couldn't be more happy with him.

    2026-06-24

  • MGH is my first choice for medical care. I have always had positive experiences with the doctors, nurses, and staff at this hospital. I now live in Florida and the joke "where do you go if you are ill? Answer- the airport ". I always add MGH to that answer.

    2026-06-24

  • Dr. Smith's approach with me allowed me to start the visit by asking what I needed or understood about where my case stood. This is in contrast to telling me things that I already knew. I think this is a bit unorthodox compared to most practitioners, but really effective in my case.

    2026-06-22

  • Excellent care by Dr. Smith. I rely on his advice totally

    2026-06-22

  • The staff, nurses and Doctor were all great. The entire team provides exceptional care!

    2026-06-21

  • Excellent care

    2026-06-21

  • Always available to explain my condition and always on time!

    2026-06-18

  • Dr Smith has provided excellent care to me for years. He understands my case history and keeps current with my tests results.

    2026-06-15

  • No problems always professional

    2026-06-14

  • Dr Smith is always on time and eager to hear my concerns. Explains everything in terms I can understand and I never feel rushed

    2026-06-15

  • Yeah, I was pleased with Dr. Smith's care and attention and yeah, I was satisfied. Thank you. Bye-bye.

    2026-06-13

  • Great experience!

    2026-06-10

  • Smith was relaxed and informative. He was in a good mood.

    2026-06-09

  • Grateful to have him on my team.

    2026-06-08

  • Dr. Smith was very knowledgeable and reassuring about my cancer and prognosis.

    2026-06-08

  • Dr. Smith has treated me for metastatic prostrate cancer for at least three decades. His skill and open manner have kept me alive. I'm unendingly grateful to him.

    2026-06-07

  • Outstanding provider.

    2026-06-07

  • Dr. Smith is a superb provider. Genuine and highly skilled. He has been a support and a great part of my cancer treatment. Always a great doctor.

    2026-06-04

  • Dr. Smith was wonderful. He knew everything about me. He's been taking care of me for years. I'm well satisfied with him. I would recommend him to anyone. Thank you.

    2026-06-03

  • It was a very pleasant experience and from start to finish, I felt as though I had good personal care and was appreciative of their professionalism and expertise.

    2026-05-29

  • I am very grateful to be in Dr. Matthew Smith's care. He gives me tremendous confidence in his knowledge and compassion for his patients.

    2026-05-27

  • All THE BEST!!!

    2026-05-27

  • Dr. Smith is a tremendous care provider. He is highly knowledgable, very empathetic, patient, and warm. He has changed my life.

    2026-05-28

  • Fortunate to have him as my doctor

    2026-05-24

  • Outstanding

    2026-05-25

  • I have been seeing Dr. Matthew Smith for ten years for prostate cancer and I would not want to change any of my experiences.

    2026-05-21

  • My care provider is outstanding.

    2026-05-21

  • Excellent. Thorough. Knowledgeable

    2026-05-18

  • Positive

    2026-05-18

  • Yes, it was a very good experience. So thank you.

    2026-05-20

  • I think Dr. Smith is a very intelligent person who fortunately prescribed the right procedures for me. I had, I guess, a serious prostate cancer problem and with the procedure that he recommended, I had 40 radiation treatments and it worked. My PSA levels went from as high as 32 down to less than 0.1. So I think that's a fantastic success rate and I'm very fortunate to have been treated by Dr. Smith.

    2026-05-20

  • Knowledgeable and caring

    2026-05-20

  • Dr. Smith was knowledgable and direct, which I very much appreciated. We were discussing the fact that my cancer isn't responding to treatment, that my future options are limited, and that I'm basically dying-in short, a difficult conversation for both of us, but necessary. I explained from the start that I appreciate clear, direct advice, not mollycoddling, and he responded in kind with a frank AND caring conversation about my current status, and how to navigate possible further treatment options. I found his approach extremely helpful in coming to terms with my prognosis and how to move forward. Hard to imagine a better conversation under those difficult circumstances. I fully appreciated his expertise, professionalism, caring, and candor.

    2026-04-30

  • Dr Smith has been directing my care for over 15 years and I have the highest confidence in him.

    2026-04-30

  • Dr. Matthew Smith is very knowledgeable and friendly. Happy to be his patient.

    2026-04-29

  • He was extremely knowledgeable on the subject, he was extremely interested in how I felt. He was kind, clear and honest in all of his comments.

    2026-04-29

  • I was very grateful for the consultation with Dr. Smith and his team. They were highly knowledgeable, respectful, personable and respectful.

    2026-04-27

  • Matthew Smith is excellent. My care is being managed by a globally recognized Dr. and great human being

    2026-04-24

  • Dr Smith knows his stuff.

    2026-04-23

  • Professional, patient-focused. The best.

    2026-04-15

  • I was super impressed with everything about this visit. Everyone positive, professional, engaged. So nice to see. The doctors...WOW! Unbelievable. So smart yet not pedantic, very concerned for me, laid it all out, no holds barred but in as nice a way as one could. I am very grateful to be part of the MGB care teams.

    2026-04-09

  • My experience was very comfortable

    2026-04-08

  • care has been very good. [redacted].

    2026-04-08

  • Dr. Smith is an absolutely superb Provider in every way.

    2026-04-06

  • open and calming communication. thank you for the reassurance

    2026-04-06

  • Excellent provider! This was scheduled as a virtual visit, but there was a scheduling issue. Nonetheless Dr. Smith took it upon himself to call me three separate times until he reached me.

    2026-04-06

  • From my first appointment to the present, Dr. Smith has been an exceptional physician. He is patient, listens to questions and is never in a rush to end an appointment. He always is professional and thoroughly goes over my care needs and progress. I've had a complex medical history. I consider myself fortunate to have Dr. Smith on my medical team.

    2026-04-01

  • Very well prepared and informed!

    2026-03-30

  • Outstanding

    2026-03-29

  • Dr. Smith is amazing in every aspect of the word.

    2026-03-29

  • Yes, Dr. Smith is very up to date on my condition and always understands what options I have available.

    2026-04-04

  • Very satisfactory. Thank you.

    2026-04-01

  • Very nice

    2026-03-31

  • Excellent

    2026-03-24

  • Dr. Smith is a wonderful physician.

    2026-03-21

  • Always professional and courteous

    2026-03-17

  • Outstanding

    2026-03-16

  • First Dr. that really seemed to care about helping me.

    2026-03-16

  • I feel very fortunate to have Dr. Matthew Smith as my primary oncologist . It was my first visit and I was very impressed . MGH is lucky to have him on your staff . He was friendly and informative .

    2026-03-15

  • All of my interactions with The provider have been excellent.

    2026-03-16

  • Dr. Smith saw me on time. Actually, he was early for the appointment. He listened attentively. He was actively engaged in my care and I'm grateful to have him looking after me.

    2026-03-14

  • Dr. Smith is a very talented and knowledgeable expert in the area of human oncology. My visit was very professional, helpful, and informative.

    2026-03-13

  • Dr Smith and his colleagues have always been great.

    2026-03-11

  • Everything was great and reassuring.

    2026-03-11

  • Dr. Smith is a very informative doctor. He will tell you everything that's going on. He will even mention things that are improvements that you can have. So that's why I like to go to Dr. Smith. Thank you very much. Bye.

    2026-03-12

  • Dr. Smith is simply two words, the best. I feel very, very fortunate and lucky to have him as my oncologist. He's great. I feel he's just the best. I really love having him as my oncologist. He said he'd support me on my decision. I'm hoping to hear back for my PCP soon and go from there. But I'm really happy that I have Dr. Matthew Smith as my oncologist. And I appreciate him helping me.

    2026-03-12

  • Excellent

    2026-03-01

  • My care provider always has always been open and easy to understand.

    2026-02-28

  • EVERYTHING WENT AS WELL AS EXPECTED

    2026-02-26

  • Dr. Smith has bern my medical oncologist for six years. He has been excellent. He explains things very well and I never hesitate to ask a question. My wife and I feel very comfortable with him and we appreciate everything he has done for us.

    2026-02-26

  • He listen very carefully to my concerns and gave me the information to continue with my cancer treatments. He is extremely knowledgeable.

    2026-02-23

  • It was a very satisfactory experience as it always is with this provider.

    2026-02-25

  • Dr. Smith is a wonderful doctor. He's extremely knowledgeable. He's personable. He takes his time for you. Wants to make sure you understand everything and wants to know if you have any questions. And I just can't say enough positive about him. And I already have recommended him to several of my acquaintances. Thank you.

    2026-02-20

  • Attention to detail and care has been excellent

    2026-02-18

  • They helped me a lot, great team!!

    2026-02-18

  • Listened and addressed all of my questions

    2026-02-14

  • I love Dr Smith. A tribute to his profession.

    2026-02-06

  • Very competent, very experienced

    2026-02-05

  • Superb. Always beyond compare. Top of his field.

    2026-02-04

  • Unbelievable the man is brilliant

    2026-02-02

  • Dr Smith is top of his field. Very approachable and thorough. I feel I am getting the best possible medical care with him on my side

    2026-02-02

  • I have been under this provider's care for18 years. He's always compassionate, empathetic, and professional topped by being a good guy.

    2026-02-02

  • The care exhibited The professionalism The positive attitude All was excellent

    2026-02-01

  • Dr Smith is gracious, professional and expresses a sincere interest in me as a person and patient.

    2026-01-25

  • Dr Matthew Smith is always professional, sincerely listens to me and answers my questions the best he can, and makes me feel that my good health really matters!

    2026-01-23

  • Noon. Good visit as always

    2026-01-23

  • Lucky to have Dr, Smith.

    2026-01-22

  • Great professional with a big heart.

    2026-01-20

  • Excellent service!

    2026-01-22

  • Dr. Smith is terrific!

    2026-01-19

  • Very professional and yet very friendly and calming and caring.

    2026-01-18

  • This was an excellent visit. Dr. Smith looked me in the eye during the whole conversation and not at epic on his computer. He answered all my questions with clarity and empathy. I was very glad to have met him.

    2026-01-02

  • Dr. Smith was very straightforward and clear in his answers to our questions.

    2025-12-29

  • I think it is very good

    2025-12-30

  • Dr. Smith was extremely helpful! He was well versed with my medical history. He was exceptionally clear and articulate about my diagnosis and answered all questions. Furthermore Dr. Smith understood at a deep level his recommendations and made them very understandable to my wife and to myself! I am so grateful for Dr. Smith's supportive demeanor and his professionalism!!!

    2025-12-29

  • I saw three doctors and they were all terrific!

    2025-12-30

  • Dr Smith gave me a strong positive explanation based on my history and what the future should hold for my slight increase in PSA increase from blood testing.

    2025-12-28

  • This provider, Dr. Matthew Smith, is the best in his field and MGH is the best medical institution in the nation.

    2025-12-25

  • Wonderful experience!

    2025-12-24

  • Dr Smith as always made me feel comfortable and relaxed. His staff asr amazing too

    2025-12-24

  • It was 30 second virtual call

    2025-12-22

  • Dr. Smith has been my health care provider for over 10 years. I don't know what I would do without him.

    2025-12-22

  • Dr. smith is giving me exceptional care and I'm delighted to be as patient

    2025-12-21

  • Outstanding with a wealth of experience in his specialty

    2025-12-21

  • Dr. Smith and his team (at least those I saw) were terrific! [redacted]

    2025-12-21

  • Dr Smith continues to provide excellent care both individually and as part of the team which has managed my cancer for quite a few years now. Through the different phases of treatment and the upheavals of COVID he has always been focused and communicative.

    2025-12-21

  • The Best

    2025-12-16

  • Great place

    2025-11-30

  • I did not have an in-house visit; it was a phone follow up conversation with my oncologist after my blood work was completed.

    2025-11-30

  • excellent

    2025-11-27

  • Excellent

    2025-11-26

  • He listened to me cause I've had a lot of side effects we had to discuss

    2025-11-27

  • excellent

    2025-11-17

  • He helped save my life !!

    2025-11-13

  • He has Great knowledge about my problem and excellent bedside manner.

    2025-11-13

  • Very good care

    2025-11-12

  • I am a cancer patient since [redacted]. I have always had a pleasant experience with MGH no matter where I am in my treatments. Happy to be with the best hospital in the world!

    2025-11-12

  • Professional, courteous.

    2025-11-10

  • Total professionalism throughout entire appointment. Carefully listened to my questions and answered them thoroughly and thoughtfully. He eases tension and enhances understanding. Also empathy is in plat.

    2025-11-10

  • This was my first meeting with Dr. Smith. He calmly and intelligently spoke with me about the condition of my health. He also recommended some blood testing and he addressed the reasons which he supported this testing. All of the foregoing was communicated in a professional and calm method that gave me confidence and calmness.

    2025-11-10

  • Dr Mathew Smith is excellent, the best in his field and I feel very comfortable taking and discussing my case with him.

    2025-11-09

  • Simply the Best!

    2025-11-09

  • I always count on Dr. Smith and his team to give me the best care possible and I'm very happy and lucky to be working with them.

    2025-10-29

  • Dr Matthew Smith has known me since 1998. He has helped prolong my life. I explained that my care at Moffitt Cancer Ctr was becoming less desirable as the months passed. I needed Dr Smith's opinion on what was happening with my body. According to the X-rays he didn't see any changes from four years ago.

    2025-10-26

  • Dr. Smith has been and is great.

    2025-10-26

  • Super thoughtful.

    2025-10-22

  • Every thing was fine, just there for a quick follow up check in visit.

    2025-10-21

  • Excellent and comprehensive care

    2025-10-14

  • Really, Dr. Smith is a leader in his field. In my case, his treatment and expertise saved my life. I would have died years ago if it weren't for him.

    2025-10-14

  • They were great. Follow up for a scan appointment was good. Very satisfied

    2025-10-13

  • Always very pleasant and takes time to answer all my concerns.

    2025-10-12

  • Explaining the procedure very clearly

    2025-10-12

  • Knowledgable and caring.

    2025-10-06

  • I could not have more confidence in Dr Matt Smith. Eight years ago and all the time since then, Dr [redacted], Dr Matt Smith and Dr [redacted] have managed the removal of my prostate and and a lymph node, and radiation and medication. They have saved my life. There is another challenge now. I am blessed that these doctors are supervising everything about the new challenge.

    2025-10-06

  • Excellent

    2025-10-01

  • Was personable and listened. Explained well

    2025-10-01

  • Very good explanations of care options and procedures. Very thorough....

    2025-09-28

  • My plan was to choose active surveillance for my prostate cancer. I didn't realize that my condition was worse than I expected until Dr. Smith explained it to me. Based on his recommendation not to delay treatment I have chosen to have radiation treatments.

    2025-09-25

  • Dr smith is thoughtful. He speaks honestly and says what he would do. This is helpful since we are not doctors and none of the choices are great

    2025-09-24

  • Always good.

    2025-09-22

  • Good

    2025-09-23

  • Matt Smith is extraordinarily knowledgeable about my cancer and provided great insight into its likely trajectory and treatment, given current information on my existing condition.

    2025-09-18

  • very attentive an nice to talk to

    2025-09-17

  • My experience was excellent.

    2025-09-14

  • I am a longtime and very satisfied patient.

    2025-09-05

  • He was extremely helpful

    2025-09-04

  • Dr. Smith has a keen grasp of my medical history and test results to reach a good plan for any future treatment.

    2025-08-25

  • a terrific doctor, knowledgeable, answers questions, in fact, tends to anticipate questions that I'm asking. And I'm very pleased with him and very grateful for his help.

    2025-08-20

Accepted Insurance

  • Tufts Medicare Preferred
  • Medicaid VT
  • Wellpoint
  • Blue Cross Blue Shield Medicare
  • WellSense NH
  • Harvard Pilgrim Health Care
  • Maine Community Health Options
  • Beech Street
  • Blue Cross Blue Shield - Indemnity
  • WellSense
  • Medicare ACO
  • Medicaid NH
  • Aetna
  • Medicaid ME
  • TriCare
  • Medicaid RI
  • Humana
  • Coventry
  • Fallon Health
  • MassHealth
  • Commonwealth Care Alliance
  • Cigna
  • Senior Whole Health
  • Tufts Health Plan
  • Multiplan
  • Mass General Brigham Health Plan
  • Railroad Medicare
  • United Health Care
  • Blue Cross Blue Shield
  • Medicare