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Center for Brain Circuit Therapeutics

The Mass General Brigham Center for Brain Circuit Therapeutics offers treatment for patients with neurological and psychiatric symptoms by identifying and modulating brain circuits to help manage symptoms.

A computer monitor displays a detailed digital rendering of a human brain scan, featuring intricate neural pathways and data overlays.

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Call to make an appointment

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Targeting neural circuits to treat brain disorders

Conditions like Parkinson’s disease, essential tremor, depression, and dystonia can interfere with movement, mood, and daily function. While medications are often the first step, they are not effective for everyone.

Our specialists identify and precisely target the brain circuits driving symptoms. We are home to one of the few centers in the world to offer the full range of neuromodulation therapies.

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Part of the Neuroscience Institute
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Our approach to care

We use advanced, targeted therapies to precisely modulate brain circuits involved in neurological and psychiatric symptoms.
A female medical provider examines a display of brain scans and points at MRI and PET images.
Multidisciplinary brain circuit modulation

The Center for Brain Circuit Therapeutics brings together experts in neurology, psychiatry, neurosurgery, and neuroradiology.

Your evaluation and treatment planning are coordinated across disciplines, often in a single day and at one location. For example, patients being evaluated for DBS may see multiple specialists and complete imaging in back-to-back appointments, allowing our team to quickly identify affected brain circuits and recommend a personalized treatment plan.

Targeted neuromodulation therapies

We treat neurological and psychiatric symptoms by focusing on the brain circuits driving them. Once we identify these circuits, we use a precise neuromodulation therapy to target them and bring them under control.

We are home to one of the few centers worldwide to offer the full spectrum of neuromodulation options, including:

  • Deep brain stimulation (DBS)
  • Transcranial magnetic stimulation (TMS)
  • MRI-guided focused ultrasound (MRg-FUS)
State-of-the-art treatment facilities

We have dedicated operating suits for all our therapies, allowing us to directly target brain circuits:

  • Operating suites for MRI-guided “asleep” DBS that do not require patients to be awake during the procedure
  • Treatment suites for MRI-guided TMS, including robotic TMS for higher accuracy and consistency
  • One of the country’s first MRgFUS suites
  • Our teams have long been leaders in neuromodulation innovation. For example, we are home to the first hospital to perform over 800 FUS procedures.
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Our approach
Our specialists treat neurological and psychiatric symptoms by identifying and targeting the brain circuits involved. Treatment recommendations are based on your symptoms, preferences, and your overall health.
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Conditions and treatments

Expertise

Advanced neurological symptom care across the Mass General Brigham Neuroscience Institute.
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Nationally recognized care
Mass General Brigham hospitals are consistently recognized by U.S. News & World Report for excellence in neurology and psychiatry.
Excellence in neuromodulation therapies
Mass General Brigham hospitals were among the first to offer brain circuit targeted neuromodulation treatments. Our specialists are among the most experienced in the world with these treatments.
Integrating research and clinical care
Mass General Brigham hospitals are leaders in research and developing new and improved neuromodulation treatments. We bring research advances into the clinic, allowing us to offer advanced treatment options not available elsewhere. We also offer a wide range of opportunities to participate in research and clinical trials.
Second opinions for complex care
We offer second opinions for patients who have previously received neurological or psychiatric treatments including DBS, TMS, and MRg-FUS but did not experience the results they hoped for. We can help reassess diagnosis, refine treatment options, and clarify next steps.
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Our neuroscience specialists

Your care is coordinated by a team of specialists in neurology, neurosurgery, advanced brain imaging, and nursing. Depending on your condition, your care team may also include experts in neuropsychology, rehabilitation, genetics, social work, and mental health. This team works together to understand your neurological condition from every angle and develop a care plan tailored to you.
An illustration of a care team.
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6177327432
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Specialists

Neuroscience clinical trials and research

Our research is shaping the future of neuroscience care. We offer access to clinical trials and emerging therapies, including treatments that may not yet be widely available. Eligibility depends on a person’s diagnosis, treatment history, and more. Explore our research and clinical trials or talk with your care team to learn about available options.
A scientist in a white lab coat holds a rack of test tubes filled with yellow liquid.
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Explore our neuroscience research

Learn how neuroscience research informs patient care

https://research.massgeneralbrigham.org/en/institutes-centers/neuroscience-institute
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Search clinical trials

Search open clinical trials for neurological conditions

https://rally.massgeneralbrigham.org/
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Explore articles featuring expert insights on neuroscience, patient experiences, and tips for managing a neurological diagnosis.

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Contact the Center for Brain Circuit Therapeutics

Call us to speak with a team member who can help you understand your options and guide you to the care that is right for you. With locations throughout New England and support for patients traveling from outside the United States, we make it easier to access coordinated, expert care.
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617-732-7432
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International Patient Services

Contact information for international patients

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