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Immune Deficiency Program
Immune deficiency diseases (immunodeficiencies) weaken your immune system, making you more prone to life-threatening infections. Our Immune Deficiency Program offers advanced treatments to help you stay well.
World-class care for immune deficiency diseases
Hundreds of immune deficiency diseases can weaken your immune system, increasing your risk of life-threatening infections. Managing immunodeficiencies requires deep expertise. At our Immune Deficiency Program, we offer personalized care for children and adults with immunodeficiencies. Other providers refer challenging cases to us because we offer the latest treatments to boost your immune system and protect against illness.
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Part of Allergy and Clinical Immunology
Learn more about allergy and clinical immunology at Mass General Brigham
Our approach to immune deficiency care
Our pediatric and adult immunologists have specialized expertise in managing immunodeficiencies. A team of specialists work collaboratively to manage all healthcare needs.
Expertise in all types of immunodeficiencies
Hundreds of immune deficiency diseases can weaken your immune system and cause infections. We offer expert care for:
- Primary immune deficiency diseases (PIDD): These inherited lifelong conditions affect children and adults.
- Secondary (acquired) immune deficiency diseases: Acquired diseases may occur after an illness or treatments for autoimmune diseases, cancer, or other conditions.
Advanced diagnostic tests
We tailor our diagnostic approach to your specific symptoms and needs. Diagnostic tests may include:
- Physical examination, with a review of your medical and family histories
- Allergy skin prick tests
- Lab tests to assess antibody and immune cell levels and function
- Screenings for chronic diseases and infections
- Vaccine challenge to check for an impaired immune system response to a vaccine
Personalized treatment
We customize your treatment based on your unique diagnosis, symptoms, and needs. We offer the latest treatments, including:
- Immunoglobulin G (IgG) replacement therapy, to infuse donated antibodies into your bloodstream and support your immune system’s natural defenses
- Medications, such as antibiotics for bacterial infections and antivirals for viral infections
- Gene therapy, to correct gene changes that cause some types of primary immunodeficiencies
- Stem cell transplant, to infuse donated immune cells into your body to support your immune system
Multidisciplinary team approach
Our world-class immunologists work closely with other specialists to manage all your healthcare needs. Your care team may include experts in:
- Autoimmune diseases (rheumatology)
- Blood disorders (hematology)
- Breathing disorders (pulmonology)
- Cancers (oncology)
- Digestive diseases (gastroenterology)
- Ear, nose, and throat conditions (otolaryngology)
- Liver problems (hepatology)
Related conditions and treatments
Our immunologists manage all types of primary immune deficiency diseases, as well as acquired immunodeficiencies. Our advanced treatments include immunoglobulin replacement therapy, gene therapy, and stem cell transplants.
- Common Variable Immunodeficiency
- Immunoglobulin A Deficiency
- IgG Deficiency
- X-Linked Agammaglobulinemia
- 22q11.2 Deletion Syndrome in Children
- Immune System Disorders
- Quantitative Immunoglobulins
- T and B Lymphocyte and Natural Killer Cell Profile
- Clinical Genetic Testing
- Haemophilus Influenzae Antibody
- Tetanus Antibody
Our specialists
No matter what disease or condition you have, Mass General Brigham has specialists near you who can help.
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617-726-3850
6177263850
Contact the Immune Deficiency Program
Call us to speak with a team member who can help you understand your options and guide you to the care that is right for you. With locations throughout New England and support for patients traveling from outside the United States, we make it easier to access coordinated, expert care.
Phone
Brigham and Women's Hospital
617-732-9850
Massachusetts General Hospital
617-726-3850
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