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Multiple Sclerosis (MS) Treatment Program

At Mass General Brigham, our multiple sclerosis specialists provide expert, coordinated care for every stage of MS. From diagnosis to advanced treatments and ongoing support, we're here to help you navigate your options and manage your health with confidence.

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Specialized MS care backed by research and expertise

Multiple sclerosis is a long-term autoimmune disease that affects the brain, spinal cord, and optic (eye) nerves. It can cause symptoms such as vision loss, difficulty with balance, and muscle weakness.

At the Mass General Brigham Neuroscience Institute, our experienced multiple sclerosis specialists care for people with all forms of MS, including complex and progressive disease.

Our team brings together expertise across specialties, advanced diagnostic tools, and access to the latest treatment options, research, and clinical trials. We work with you to develop a personalized care plan focused on managing symptoms, slowing disease progression, and maintaining independence and quality of life.

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Part of the Neuroscience Institute
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Our approach to multiple sclerosis care

From your first evaluation through ongoing treatment, our specialists combine research-driven care, advanced therapies, and coordinated support to meet your changing needs.
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Expert diagnosis and treatment planning

Our MS specialists use neurological evaluations, MRI scans, and other diagnostic tests to understand your condition.

Whether you're seeking an initial diagnosis or a second opinion, we work with you to develop a treatment plan based on your symptoms, medical history, and goals.

Advanced MS treatments and infusion care

We offer a range of disease-modifying therapies to help reduce relapses and slow disease progression. Depending on your needs, treatment may include oral medications, injections, or infusions.

Our team helps you understand your options, what to expect during treatment, and how we'll monitor your progress.

Coordinated care and ongoing support
Managing MS often involves more than medication. Our neurologists work with rehabilitation specialists, physical and occupational therapists, and other providers to address challenges such as fatigue, weakness, mobility changes, and emotional well-being.
Personalized care at every stage

At your first visit, we'll review your medical history, perform a neurological exam, discuss prior testing, and develop a personalized treatment plan.

During follow-up visits, we'll monitor your symptoms, assess your response to treatment, and adjust your care as needed.

Your ongoing care may include medication to delay disease progression or manage specific symptoms or flare-ups, physical and occupational therapy, and other support to help you manage MS and maintain your independence and quality of life.

Research-driven MS care

We use the latest technology and research to provide accurate diagnoses and effective care, including advanced onsite imaging, biomarker panels that may identify relapses, and onsite infusion medication delivery.

Our researchers are also conducting cutting-edge clinical trials that address the care needs of people with relapsing and progressive MS.

Specialized MS care close to home
With locations across the state, we make it easier to access expert MS care closer to home. Our specialists work together across Mass General Brigham to coordinate treatment, monitoring, and ongoing support, helping you benefit from the expertise of our broader health system while reducing the need to travel for every appointment.

Multiple sclerosis conditions and treatments

Explore the types of multiple sclerosis and the therapies available to help manage symptoms, reduce relapses, and slow disease progression. Your care team will work with you to select an approach based on your form of MS, health needs, and goals.

Neuroscience care near you

Mass General Brigham delivers neurological and neurosurgical care across New England, offering convenient access to care close to home with seamless connection to specialized services.
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View multiple sclerosis care locations
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Patient story

25 Boston Marathons later: Why multiple sclerosis has failed to stop this runner

After being diagnosed with multiple sclerosis, Jan Fuller feared she would have to give up running. But with support from her Mass General Brigham care team, she went on to complete 25 Boston Marathons. Discover how expert, coordinated care has helped Jan stay active and continue doing what she loves.
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Read Jan's story

Read Jan's multiple sclerosis patient story

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Neuroscience clinical trials and research

Our research is shaping the future of neuroscience care. We offer access to clinical trials and emerging therapies, including treatments that may not yet be widely available. Eligibility depends on a person’s diagnosis, treatment history, and more. Explore our research and clinical trials or talk with your care team to learn about available options.
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Explore our neuroscience research

Learn how neuroscience research informs patient care

https://research.massgeneralbrigham.org/en/institutes-centers/neuroscience-institute
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Search clinical trials

Search open clinical trials for neurological conditions

https://rally.massgeneralbrigham.org/