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Biobank Genomics Core

Next-Generation Sequencing

We offer next-generation sequencing for a range of sequencing read lengths and coverage as well as library construction services.

Biobank Genomics Core next-generation sequencing

The Biobank Genomics Core at Mass General Brigham Personalized Medicine has a strong history of producing the highest quality data for collaborators and clients. Our goal is to help investigators advance their basic and translational research programs by providing exceptional service, technical expertise, and leading sequencing technologies.

We offer next-generation sequencing on the Illumina NovaSeq X Platform, offering a range of sequencing read lengths and coverage for customer produced libraries, as well as for incoming DNA or RNA for our suite of library construction services.

At your service

At Mass General Brigham Personalized Medicine Biobank Genomics Core (BGC), we offer genotyping and next generation sequencing services to support your project. With over a decade of experience and a proven track record of helping Mass General Brigham investigators achieve their research aims, our goal is to make sequencing/genotyping technologies accessible to the research community.

Our services are listed below. Please contact us for additional information on any of our services, or for pricing. We also provide support documentation (letter of support, workflow description, quotes) to support grant applications.

Biobank Genomics Core services

  • Whole genome sequencing
  • Exome sequencing
  • RNASeq
  • Small RNAseq (miRNASeq)

  • Alignment/Variant calling and Variant annotations
  • Gene/Transcript counts and differential expression analysis for RNAseq

Accounts and ordering

All our projects are managed via our customer portal, Mass General Brigham PCMS.

After creation of a PCMS service order please contact us to coordinate delivery of your samples. We only receive samples Monday through Friday 9 am-12 pm and 1 pm-4 pm. Please bring all service request paperwork with you.

For more information on PCMS, please review our placing orders FAQ.

Please contact us for more information.

Sample requirements are platform and service specific. We are happy to provide you details based on your specific project and work with you to explore your needs.

Please contact our Core Labs for more information.

Mass General Brigham Personalized Medicine
65 Landsdowne St., 3rd floor
Cambridge, MA 02139-4232
Directions

You will be contacted when data is available. Depending on size, data will be available for download, or can be shipped to you on an external hard drive. Data will remain available from Personalized Medicine for three months.

Please contact the lab if you need information about your specimens or any study-specific information.

Data delivery

Options

  • ERISOne DropBox
    • Preferred data delivery method for internal (Mass General Brigham) customers
    • Requires an ERISOne account and a comfort working within a Linux environment
  • Mass General Brigham Transfer Utility
    • Available for external customers and internal customers without ERISOne accounts
    • Limited to 100GB per transfer
  • Encrypted external hard drives

Policy

There is no cost for the initial delivery of project data. Additional charges will apply for the retrieval and delivery of archived data. The estimated turnaround time for the repeated delivery of archived data is one to two weeks.

Bioinformatics advanced services: We offer additional bioinformatics support for both sequencing and biobank projects. Please email us for information on pricing.

Contact us

For Illumina Next-Gen Sequencing, genotyping quotes, and customer inquiries, please email PPMCore@partners.org

For DNA/RNA extraction, sample handling service quotes, and customer inquiries, please email PPMCENTRALBIOBANK@partners.org